On the opening lap of the fourth segment, a mechanical failure in Jeff Gordon's car sent the No. 24 Chevy into the outside wall in Turn 3, collecting the Chevrolet of Martin Truex Jr. and the Ford of Greg Biffle.
Kahne had two brushes with the wall in segment No. 4, ending his strong run with the sort of disappointment that has plagued him in points races all season long.
With the best average finish in the first four segments, Harvick entered pit road first for a mandatory four-time stop before the final 10-lap dash. McMurray, who made a huge track position gain by staying out between the third and fourth segments, was second onto pit road, followed by Johnson, Earnhardt Jr. and Edwards.
But Edwards used the No. 1 pit stall to advantage, winning the race off pit road over McMurray and Harvick. Kenseth started the final segment in the fourth spot, with Johnson and Earnhardt behind him in fifth and sixth.
Edwards, however, could not keep McMurray behind him, and after watching replays of the battle, the driver of the No. 99 Roush Fenway Racing Ford was already second-guessing himself.
"Jamie just did a perfect job on the start," Edwards said. "I had him cleared for a minute. If I would have pulled in front of him in Turn 1, if I would have gone high, I think we would have won that race, but I was just so reluctant to give up the bottom.
"Jamie just did a perfect job. He ended up sweeping around the outside of me, dragging me down, and it was a drag race. My hat is off to him. He did a great job. He earned it.
"I drove as hard as I could while he was on the outside and he gave me just the right amount of room to not wreck me, but still beat me. If I had it to do over again, I'd do it differently, but that's racing. You've just got to make the best decision you can and move on. It's a really tough one, though."
Though Edwards and McMurray inched ahead of each other at various junctures after then final restart, McMurray led at the finish line for each of the final 10 laps. Once he cleared Edwards three laps into the run, McMurray pulled away.