CINCINNATI -- Travis Wood pitched six shutout innings, and first baseman Anthony Rizzo and center fielder Arismendy Alcantara homered, lifting the Chicago Cubs to a 3-0 victory over the Cincinnati Reds in the opener of a three-game series Tuesday night at Great American Ball Park.

Wood (8-11) allowed only two hits and a walk, striking out five, over 96 pitches. Hector Rondon earned his 22nd save.

The Cubs (59-72) have won four straight and six of eight.

There weren't many hard-hit balls off Wood, who retired Cincinnati in order in the second, third and sixth innings. He held the Reds without a hit in four of his six innings.

Reds starter Johnny Cueto (15-8) gave up three earned runs on seven hits. Cueto walked two and fanned eight. He allowed two homers in a game for the fourth time this season.

Cincinnati (63-69) has lost eight of 10 and is 12-25 since the All-Star break.

With two outs in the first, Rizzo launched a 2-1 pitch from Cueto into the right-center field stands putting the Cubs ahead 1-0. It was his 30th home run this season.

Moments later, the skies opened up over Great American Ball Park resulting in a 50-minute rain delay.

Neither starting pitcher seemed fazed by the interruption.

Cueto retired 10 in a row and Wood set down 10 straight following a one-out single by first baseman Todd Frazier in the first. Each pitcher allowed only two hits through five innings.

Chicago held a precarious 1-0 lead through six innings, before right fielder Matt Szczur singled and scored on Alcantara's home run, his fifth this season, which made the score 3-0.

NOTES: Cubs manager Rick Renteria said he's eager to see how OF Jorge Soler adapts to the major leagues. Soler, the club's fifth-ranked prospect according to MLB.com, is expected to be recalled from Triple-A Iowa on Wednesday. "It's pretty exciting for the whole organization," Renteria said. "He's a young man who's been talked about quite a bit. He's a gifted outfielder with some power." ... Cubs SS Starlin Castro rejoined the club from the bereavement list on Tuesday and INF Logan Watkins was optioned to Triple-A Iowa. Castro had returned to the Dominican Republic after an auto accident claimed the life of a relative and three friends. "He looks like he's in a good place," Renteria said. ... Reds RHP Homer Bailey's hopes of pitching again this season are fading. "He's not knocking on the door to start throwing," Reds manager Bryan Price said. Bailey's been on the disabled list since Aug. 16 with a strained right elbow. ... Cubs OF Justin Ruggiano missed his second straight game with a sore left ankle.