San Antonio had its seven-game postseason winning streak snapped, as well as a six-game NBA Finals win streak that dated to the 2005 finals.
Duncan, who started 0 of 5 in the opener before finishing with 20 points and 14 rebounds, began 1 for 5 in this one. But he never got untracked, though part of the problem was the Spurs' inability to get him the ball enough because of their turnovers.
Wade finished with 10 points and six assists. Miami committed just six turnovers.