Cubs 3, Reds 0: Anthony Rizzo and Arismendy Alcantara homered and Travis Wood pitched six scoreless innings as visiting Chicago won the opener of a three-game series.

Wood (8-11) snapped a 12-start winless streak, striking out five and allowing just a pair of singles, and Hector Rondon pitched a perfect ninth for his 22nd save. Starlin Castro went 2-for-4 in his return from the bereavement list for the Cubs, who have won four straight.

Reds starter Johnny Cueto (15-8) allowed three runs and seven hits over 6 1/3 innings, losing to the Cubs for the first time since 2011 and snapping a streak of five straight victories against them. Todd Frazier, Zack Cozart and Skip Schumaker each had a single for the Reds.

Rizzo blasted his 30th home run to center field in the first just before heavy rain settled in and prompted a delay. Matt Szczur singled to lead off the seventh and Alcantara followed with a two-run shot to right.

Cincinnati got the tying run to the plate in the eighth, as Schumaker beat out a bunt single with two outs and Pedro Strop walked Billy Hamilton before getting an inning-ending grounder from Frazier. Wood gave up a one-out single to Frazier in the first before retiring 10 straight and 17 of 19.

GAME NOTEBOOK: The game was delayed 50 minutes by rain in the first inning. … Rizzo exited in the eighth inning with lower back tightness. … Cubs pitchers have allowed four runs during their four-game winning streak and have surrendered only four hits in the past two contests.